Format

Send to

Choose Destination
See comment in PubMed Commons below
Fitoterapia. 2013 Jun;87:89-92. doi: 10.1016/j.fitote.2013.03.019. Epub 2013 Apr 2.

Japonicasins A and B, two new isoprenylated flavanones from Sophora japonica.

Author information

  • 1School of Pharmacy, Xinxiang Medical University, Xinxiang 453003, People's Republic of China.

Abstract

Two new flavanones with a C15 isoprenoid group, japonicasins A and B (1 and 2), were isolated from the leaves of Sophora japonica. This is the first report on the presence of the (2E,7E)-6-isopropyl-3,9-dimethyldeca-2,7,9-trien-1-yl group (C15 isoprenoid group) in isoprenylated flavonoids. Their structures were determined by spectroscopic methods, including UV, IR, 1D and 2D NMR, HRESIMS, and CD experiments. In addition, the antioxidant activities of compounds 1 and 2 were determined through DPPH radical scavenging assays. They exhibited potential antioxidant activities, with IC50 values of 35.1±0.8 μM and 88.7±1.1 μM for compounds 1 and 2, respectively.

Copyright © 2013 Elsevier B.V. All rights reserved.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk