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Neth Heart J. 2013 May;21(5):245-8. doi: 10.1007/s12471-013-0393-z.

Microsphere embolisation as an alternative for alcohol in percutaneous transluminal septal myocardial ablation.

Author information

  • 1Department of Cardiology, Thoraxcenter, Erasmus MC, 's-Gravendijkwal 230, 3015 CE, Rotterdam, the Netherlands.

Abstract

BACKGROUND:

Percutaneous transluminal septal myocardial ablation using microsphere embolisation is a new interventional technique to treat patients with hypertrophic obstructive cardiomyopathy.

METHODS AND RESULTS:

In two patients, considered at high risk for myectomy, targeted septal perforators were occluded with microsphere embolisation instead of alcohol ablation to reduce left ventricular outflow gradient. In both cases the left ventricular outflow tract gradient was immediately reduced. No adverse events occurred.

CONCLUSION:

This is the first clinical experience with Embozene® Microspheres in the Netherlands as an alternative for alcohol septal ablation. In both cases it resulted in immediate improvement in the haemodynamics, without any adverse events.

PMID:
23550029
[PubMed]
PMCID:
PMC3636334
Free PMC Article
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