Send to:

Choose Destination
See comment in PubMed Commons below
Analyst. 2013 Jun 7;138(11):3097-103. doi: 10.1039/c3an00119a.

Applications of ambient mass spectrometry in high-throughput screening.

Author information

  • 1Beijing National Laboratory for Molecular Science, Institute of Analytical Chemistry, Peking University, Beijing 100871, China.


The development of rapid screening and identification techniques is of great importance for drug discovery, doping control, forensic identification, food safety and quality control. Ambient mass spectrometry (AMS) allows rapid and direct analysis of various samples in open air with little sample preparation. Recently, its applications in high-throughput screening have been in rapid progress. During the past decade, various ambient ionization techniques have been developed and applied in high-throughput screening. This review discusses typical applications of AMS, including DESI (desorption electrospray ionization), DART (direct analysis in real time), EESI (extractive electrospray ionization), etc., in high-throughput screening (HTS).

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Royal Society of Chemistry
    Loading ...
    Write to the Help Desk