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Cleve Clin J Med. 2013 Apr;80(4):225-33. doi: 10.3949/ccjm.80a.12182.

Carbapenem-resistant Enterobacteriaceae: a menace to our most vulnerable patients.

Author information

  • 1Research Service, Louis Stokes Cleveland Department, of Veterans Affairs Medical Center, Cleveland, OH, USA.

Abstract

The emergence of carbapenem-resistant Enterobacteriaceae (CRE) highlights the importance of effective antibiotics to maintain the safety of our health care system. Clinicians will encounter CRE as a cause of difficult-to-treat and often fatal infections in hospitalized patients. We review the mechanisms of carbapenem resistance, the dissemination and clinical impact of these resistant organisms, and challenges to their detection, treatment, and control.

PMID:
23547093
[PubMed - indexed for MEDLINE]
PMCID:
PMC3960994
Free PMC Article
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