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Org Lett. 2013 Apr 19;15(8):1874-7. doi: 10.1021/ol400526a. Epub 2013 Apr 1.

An expedient route to imidazo[1,4]diazepin-7-ones via a post-Ugi gold-catalyzed heteroannulation.

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  • 1Laboratory for Organic & Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, University of Leuven (KU Leuven), Celestijnenlaan 200F, B-3001 Leuven, Belgium.

Abstract

A novel diversity-oriented post-Ugi/gold(I)-catalyzed heteroannulation process for the synthesis of imidazo[1,4]diazepin-7-ones is elaborated. The scope and limitations of the protocol are discussed.

PMID:
23544989
[PubMed - indexed for MEDLINE]
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