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Rev Med Suisse. 2013 Mar 6;9(376):502, 504-7.

[Hypertrophic cardiomyopathy in 2013].

[Article in French]

Author information

  • 1Centre de cardiologie non invasive, Hôpital de la Tour, Avenue J.-D. Maillard Ibis, 1217 Meyrin.


Hypertrophic cardiomyopathy is the most common genetic heart disease. It is caused by a variety of mutations in genes encoding sarcomeric proteins. Clinical presentation is heterogeneous just as the clinical course, ranging from asymptomatic forms to sudden cardiac death in the young. The latter is an unpredictable, fortunately rather uncommon, complication with no reliable preventive treatment. The complexity lies in the identification of high risk patients who could benefit from an implantable cardioverter-defibrillator in primary prevention. Symptomatic patients presenting left ventricular outflow tract obstruction despite optimal medical treatment may undergo surgical septal myectomy or percutaneous alcohol septal ablation.

[PubMed - indexed for MEDLINE]
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