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J Arthroplasty. 2013 Sep;28(8):1254-8. doi: 10.1016/j.arth.2012.12.021. Epub 2013 Mar 20.

Infection rate following total joint arthroplasty in the HIV population.

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  • 1Department of Orthopaedic Surgery, New York University Hospital for Joint Diseases, New York, New York, USA.


The purpose of this study is to review a large series of HIV-infected patients who underwent total joint arthroplasty and identify potential risk-factors for infection. Sixty-nine HIV-infected arthroplasty cases were analyzed with 138 matched controls. Deep infection rate following total hip or knee arthroplasty was 4.4% (3 of 69) among HIV cases compared to 0.72% (1 of 138) among controls, yielding a non-significant 6.22 times increased odds of infection (95% CI 0.64-61.0, P=0.11). Kaplan-Meier survival curves for infection free survival and revision free survival revealed non-significantly decreased survival in HIV cases compared to controls (P=0.06 and P=0.09). Our results suggest that the rate of early joint infection following primary total joint arthroplasty in the HIV-infected population is lower than reported in a number of previously published studies.

Copyright © 2013 Elsevier Inc. All rights reserved.


arthroplasty; hip; human immunodeficiency virus (HIV); infection; knee

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