Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Ophthalmic Inflamm Infect. 2013 Jan 15;3(1):15. doi: 10.1186/1869-5760-3-15.

Bilateral ischemic maculopathy in acquired immune deficiency syndrome.

Author information

  • 1Associated Retina Consultants Ltd, 7600 N 15th Street, Suite #155, Phoenix, AZ, 85020, USA. keen_268@yahoo.com.

Abstract

BACKGROUND:

This brief report aims to report a case of bilateral macular ischemia as a cause of sudden decreased vision in a patient with acquired immune deficiency syndrome (AIDS).

FINDINGS:

A 26-year-old male with disseminated cryptococcal meningitis, Candida thrush, Pneumocystis jiroveci pneumonia, and positive human immunodeficiency virus (HIV) infection with CD4 count of 4 cells/μl complained of sudden blurred vision in both eyes while on treatment with systemic antiviral, antifungal, and antibiotic medications. Ocular examination revealed HIV retinopathy changes with significant macular ischemia in both eyes, which was confirmed by fluorescein angiography. One dose of intravitreal foscarnet (1.2 mg/0.1 cc) was injected in both eyes. Laboratory work-up of serum and vitreous samples showed negative cytomegalovirus (CMV) titers. At 2 weeks of follow-up, he was started on treatment with atripla, a combination anti-retroviral therapy for AIDS. At 6 weeks of follow-up, there was an improvement in visual acuity and clinical findings.

CONCLUSIONS:

Noninfectious HIV retinopathy in AIDS is common, but bilateral macular ischemia is a rare presentation. It is important to rule out CMV retinitis as it is a major cause of visual morbidity among AIDS patients.

PMID:
23514376
[PubMed]
PMCID:
PMC3605083
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Springer Icon for PubMed Central
    Loading ...
    Write to the Help Desk