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Clin Nucl Med. 2013 Aug;38(8):643-5. doi: 10.1097/RLU.0b013e31827087af.

Accidental finding of bladder cancer in 99mTc methylene diphosphonate whole-body bone scan.

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  • 1Department of Nuclear Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.


A 53-year-old woman with a history of nasopharyngeal carcinoma underwent (99m)Tc methylene diphosphonate (MDP) whole-body scintigraphy for tumor staging. An MDP-avid lesion located in the urinary bladder was found. Computed tomography showed a protruding mass with calcific surface in the left inferolateral wall of the urinary bladder. A biopsy was conducted and the pathological report confirmed the diagnosis of transitional cell carcinoma. The patient received transurethral resection and Bacillus Calmette-Guérin intravesical therapy. Four months later, she underwent an (18)F-FDG PET/CT scan. Unfortunately, tumor recurrence in the bladder cancer was diagnosed by the (18)F-FDG PET/CT scan.

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