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Cell Res. 2013 May;23(5):590-1. doi: 10.1038/cr.2013.41. Epub 2013 Mar 19.

Traffic control at the "Gut-GALT crossroads".

Author information

  • 1Division of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.

Abstract

In mice treated with antibiotics to deplete commensal microbiota, there is a significant overhaul of host cellular disposition and function with CX3CR1+ mononuclear phagocytic cells carrying pathogenic and non-pathogenic administered bacteria to the (messenteric lymph node) MLN, resulting in T cell stimulation and IgA production.

PMID:
23507970
[PubMed - indexed for MEDLINE]
PMCID:
PMC3641601
Free PMC Article
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