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J Cutan Pathol. 2013 Jul;40(7):661-6. doi: 10.1111/cup.12131. Epub 2013 Mar 18.

Maffucci syndrome with the spindle cell hemangiomas in the mucosa of the lower lip: a rare case report and literature review.

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  • 1Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, P R China.

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  • J Cutan Pathol. 2013 Aug;40(8):777.


The presence of non-cutaneous vascular lesions in the syndrome of multiple enchondromas and subcutaneous hemangiomas, also named Maffucci syndrome, is exceedingly rare. Until now, non-cutaneous vascular lesions have been described in nine patients, while only three cases were present in the oral cavity; they were found in the tongue in two patients and in the lower lip in one patient. Herein, we report the second case of vascular lesions localized in the mucosa of lower lip in a patient with Maffucci syndrome. Histopathologic examination showed spindle cell hemangioma.

© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

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