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Glob Health Action. 2013 Mar 15;6:19570. doi: 10.3402/gha.v6i0.19570.

Determinants of antiretroviral treatment adherence among HIV/AIDS patients: a multisite study.

Author information

  • 1Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam. bach@hmu.edu.vn

Abstract

INTRODUCTION:

Adherence to antiretroviral treatment (ART) is vital in achieving virological treatment success. This study assessed the prevalence of optimal ART adherence and its determinants among HIV/AIDS patients in Vietnam.

METHOD:

A cross-sectional survey was conducted with 1,016 HIV/AIDS patients at seven hospitals and health centers providing antiretroviral treatment services in three provinces, including Hanoi, Hai Phong, and Ho Chi Minh City. Self-reported medication adherence was measured using a 30-day visual analog scale (VAS) and 7-day missed-doses questions.

RESULTS:

The mean adherence VAS-score was 94.5 out of 100 (SD=8.2), ranging from 40 to 100%. The rate of suboptimal adherence was 25.9%. The rate of missed-doses was 25.2%. In multivariate analysis, increased perceived self-efficacy, use of mobile phone alarms, and reminders from family members were associated with optimal adherence; higher CD4 level, single status, and unstable employment were associated with suboptimal adherence.

CONCLUSION:

High rate of suboptimal adherence observed in this study highlights the importance of adherence support interventions during ART. The use of mobile phone reminders, involvement of relatives, and HIV self-management training programs have the potential to improve ART adherence in Vietnam.

KEYWORDS:

HIV/AIDS; Vietnam; adherence; adherence aid; antiretroviral treatment; drug users

PMID:
23497956
PMCID:
PMC3600425
[PubMed - indexed for MEDLINE]
Free PMC Article
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