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Saudi J Anaesth. 2012 Oct-Dec;6(4):426-8. doi: 10.4103/1658-354X.105899.

Can entropy predict neurologic complications after cardiac surgery?

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  • 1Department of Anaesthesia and Surgical ICU, College of Medicine, University of Dammam, Al Khubar, Saudi Arabia.


Electroencephalography can detect both cerebral ischemia/hypoxia and seizures and can measure hypnotic effects. The author reported two patients with left main coronary artery disease and myocardial infarction scheduled for urgent coronary artery bypass grafting surgery; they developed abrupt decreases in response entropy (RE) and state entropy (SE) values to isoelectric silence during target-controlled propofol-sufentanil anesthesia. After that, low RE and SE values persisted throughout the intraoperative period. Both patients showed delayed awakening after surgery and brain CT revealed nonhemorrhagic tempro-parietal cerebral infarctions. Intraoperative entropy-based monitoring could predict poor neurological outcome after cardiac surgery during target-controlled propofol and sufentanil anesthesia.


Cardiac surgery; entropy; neurologic outcome; stroke

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