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J Colloid Interface Sci. 2013 May 1;397:39-44. doi: 10.1016/j.jcis.2013.01.063. Epub 2013 Feb 8.

Carbon-dots derived from nanodiamond: photoluminescence tunable nanoparticles for cell imaging.

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  • 1Department of Chemistry and the Tsinghua Center for Frontier Polymer Research, Tsinghua University, Beijing 100084, PR China.


Water dispersible carbon-dots (CDs) with tunable photoluminescence were synthesized via one-pot hydrothermal oxidation of nanodiamond and subsequently utilized for cell imaging applications. The CDs were characterized by the following techniques including transmission electron microscopy, atomic force microscopy, Fourier transform infrared spectroscopy, UV-Visible spectroscopy, and fluorescent spectroscopy. Results showed that the size of CDs is mainly distributed at 3-7 nm. Many functional groups were introduced on the surface of CDs during hydrothermal oxidation procedure. Cell morphology observation and cell viability measurement demonstrated the good biocompatibility of CDs, suggesting their potential bioimaging applications.

Copyright © 2013 Elsevier Inc. All rights reserved.

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