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Angiology. 2013 Nov;64(8):627-32. doi: 10.1177/0003319713480424. Epub 2013 Mar 7.

Association between coronary artery ectasia and neutrophil-lymphocyte ratio.

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  • 11Department of Cardiology, Gulhane Medical Academy, Ankara, Turkey.

Abstract

Atherosclerosis plays an important role in the etiopathogenesis of coronary artery ectasia (CAE). Inflammation markers may play a part in the pathogenesis of CAE. We aimed to assess the association between the CAE and the neutrophil-lymphocyte (N/L) ratio. Consecutive eligible patients (n = 181) were divided into 3 groups: patients with CAE, those with newly diagnosed coronary artery disease (CAD), and those with a normal coronary angiogram. The N/L ratio and mean platelet volume (MPV) were measured as part of the automated complete blood count. There were no statistically significant differences in N/L ratio and MPV between the CAE and the CAD groups. The N/L ratio and MPV were significantly higher in patients in both CAE and CAD groups compared to those in the control group (P < .01). An increased N/L ratio may play a role not only in the pathogenesis of CAD but also in the pathophysiology of CAE.

KEYWORDS:

atherosclerosis; coronary artery ectasia; mean platelet volume; neutrophil/lymphocyte ratio

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