A 50-year-old woman developed a slowly progressive inability to control her motor functions over the past 3 years. For example, she would close the refrigerator door immediately after opening it against her intension, or at intersections she would go in a direction that she did not intend. These symptoms were regarded as "conflict of intentions (COI)." Brain magnetic resonance imaging (MRI) revealed diffuse atrophy of the corpus callosum with hyperintense lesions in the rostral portion of its body and the splenium. Based on these findings, her COI could be attributable to leukodystrophy of an unknown origin.