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Am J Gastroenterol. 2013 May;108(5):811-7. doi: 10.1038/ajg.2013.47. Epub 2013 Mar 5.

A randomized controlled trial of an online intervention to improve gluten-free diet adherence in celiac disease.

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  • 1Clinical Psychology Unit, The University of Sydney, Sydney, New South Wales, Australia.

Abstract

OBJECTIVES:

To test the effectiveness of an interactive online intervention to improve gluten free diet adherence in adults with celiac disease.

METHODS:

A Randomized controlled trial was conducted. A total of 189 adults with biopsy-confirmed celiac disease were recruited and randomized to receive the intervention (n=101) or to a waitlist control condition (n=88). Post-intervention data was available for 70 intervention and 64 waitlist participants. Three month follow-up data was obtained for 46/50 completers from the intervention group. The primary outcome measure was gluten-free diet adherence. Secondary outcomes were gluten-free diet knowledge, quality of life and psychological symptoms.

RESULTS:

Results were based on intention-to-treat analyses. The intervention group evidenced significantly improved gluten-free diet adherence, and gluten-free diet knowledge following the treatment period relative to the waitlist control group. The change in knowledge did not contribute to the change in adherence. These improvements were maintained at 3-month' follow-up.

CONCLUSIONS:

The online program was effective in improving adherence and represents a promising resource for individuals with celiac disease who are struggling to achieve or maintain adequate gluten free diet adherence.

PMID:
23458849
[PubMed - indexed for MEDLINE]
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