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Nat Prod Res. 2013 Oct;27(20):1877-81. doi: 10.1080/14786419.2013.771352. Epub 2013 Mar 4.

Tricycloalternarene derivatives from endophytic fungus Alternaria tenuissima SY-P-07.

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  • 1a School of Traditional Chinese Materiel Medica, Shenyang Pharmaceutical University , Shenyang , 110016 , People's Republic of China.


A new tricycloalternarene, TCA 11a (1), was isolated from the culture broth of an endophytic fungus, Alternaria tenuissima SY-P-07, along with four known structurally related compounds 2-5. The structure of compound 1 was elucidated by extensive spectroscopic methods, especially 2D NMR, and the absolute stereochemistry of 1 was suggested on the basis of the CD spectral analysis and NOESY data.

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