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Chem Pharm Bull (Tokyo). 2013;61(3):366-9.

New bisabolane sesquiterpene from the mycelia of Amanita virgineoides.

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  • 1Graduate School of Biomedical Sciences, Division of Natural Product Chemistry, Nagasaki University, Nagasaki, Japan.


A bisabolane type of sesquiterpene was isolated from the culture medium of Amanita virgineoides BAS, together with two known compounds, including lignoren, and harziandion. The structure of the new compound "virgineol" was established using a combination of different NMR spectroscopy techniques, whereas the chemical structure of the known compound was identified as lignoren, and the structure of harziandion was confirmed by X-ray crystallographic analysis.

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