Quality of life among people with epilepsy: a cross-sectional study from rural southern India

Natl Med J India. 2012 Sep-Oct;25(5):261-4.

Abstract

Background: Epilepsy can be associated with profound physical, social and psychological consequences and it has an impact on a person's quality of life. We assessed the quality of life and factors associated with a poor quality of life, among adults with epilepsy in a rural block of Tamil Nadu.

Methods: We interviewed 91 epilepsy patients from 20 randomly selected villages using a structured questionnaire including World Health Organization Quality of Life BREF (WHOQOL-BREF), Patient Health Questionnaire 2 (PHQ-2) and Generalized Anxiety Disorder 7 (GAD-7) questionnaires.

Results: The mean (SD) total score of the quality of life scale was 61.49 (12.56). Those who were single, separated or widowed (t statistic= -2.71, p<0.01), had not completed primary education (t statistic=-2.308, p<0.05), not currently going for work (t statistic=-2.748, p<0.01), had seizure in the past one year (t statistic=-4.068, p<0.01),had depressive symptoms (t statistic=-3.207, p<0.01),had higher anxiety scores (t statistic=-2.727, p<0.01), had low scores in the quality of life questionnaire. Multivariate analysis showed increasing age, education less than grade V, being unmarried, widowed or separated, lower per capita income, a high anxiety score and experiencing a seizure episode in the past one year to be significantly associated with a low score in the WHOQOL-BREF questionnaire (adjusted R²=0.378, SE 9.90).

Conclusion: The presence of anxiety, lack of primary education, being single, separated or widowed, increasing age, low per capita income and having a seizure episode in the past year are associated with lower quality of life among people with epilepsy.

MeSH terms

  • Adult
  • Age Factors
  • Anxiety / epidemiology
  • Anxiety / psychology
  • Cross-Sectional Studies
  • Depression / epidemiology
  • Depression / psychology
  • Educational Status
  • Employment / psychology
  • Employment / statistics & numerical data
  • Epilepsy / psychology*
  • Female
  • Humans
  • Income / statistics & numerical data
  • India / epidemiology
  • Male
  • Marital Status / statistics & numerical data
  • Middle Aged
  • Multivariate Analysis
  • Quality of Life*
  • Risk Factors
  • Rural Population / statistics & numerical data
  • Surveys and Questionnaires