Format

Send to:

Choose Destination
See comment in PubMed Commons below
Org Lett. 2013 Mar 15;15(6):1166-9. doi: 10.1021/ol4001087. Epub 2013 Feb 27.

Entry to β-alkoxyacrylates via gold-catalyzed intermolecular coupling of alkynoates and allylic ethers.

Author information

  • 1Department of Chemistry, Pohang University of Science and Technology, Hyoja-dong San 31, Pohang, Kyungbuk 790-784, Republic of Korea.

Abstract

The first gold-catalyzed intermolecular coupling of alkynoates and allylic ethers invoking alkoxy addition and [3,3]-sigmatropic rearrangement as the key mechanism has been developed. Remarkably, the reaction showed complete chemoselectivity toward the pathway initiated by the alkoxy addition to alkynes. This unprecedented reactivity led to a new access to diversely substituted β-alkoxyacrylates in a highly efficient manner.

PMID:
23444917
[PubMed]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society
    Loading ...
    Write to the Help Desk