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J Neurosurg. 2013 Jul;119(1):86-93. doi: 10.3171/2012.12.JNS11539. Epub 2013 Feb 22.

Modern surgical outcomes following surgery for sphenoid wing meningiomas.

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  • 1Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, California 94143, USA.



Cushing and Eisenhardt were the first to describe sphenoid wing meningiomas in detail, categorizing globoid tumors into 3 groups: 1) medial; 2) middle; and 3) lateral. The authors review their experience with resection of sphenoid wing meningiomas at a single center, to examine whether this classification predicts clinical presentation and postsurgical outcome.


All patients undergoing resection of sphenoid wing meningioma at the authors' institution over a 9-year period were identified. Clinical data were compared from patients with tumors arising at different points along the sphenoid wing to determine if these tumors behaved differently in terms of symptoms, radiographic characteristics, and postsurgical outcome.


A total of 56 patients underwent microsurgical resection for sphenoid wing meningioma during this period. The rates of optic canal invasion (medial 50% vs middle 5% vs lateral 0%; p<0.0001, chi-square test), supraclinoid internal carotid artery encasement (medial 32% vs middle 5% vs lateral 0%; p<0.01, chi-square test), and middle cerebral artery encasement (medial 45% vs middle 24% vs lateral 0%; p<0.01, chi-square test) were all highest with medial-third tumors. New or worsened neurological deficits occurred in 10 (19%) of 56 patients. Of all the imaging characteristics studied, only location of the tumor along the medial third of the sphenoid wing significantly predicted an increased rate of new or worsened neurological deficit (OR 2.7, p<0.05).


The authors report outcomes in a large series of sphenoid wing meningiomas that were treated using modern surgical techniques.

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  • Sphenoid wing meningiomas. [J Neurosurg. 2013]
  • Response. [J Neurosurg. 2013]
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