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J Antimicrob Chemother. 2013 Jul;68(7):1465-70. doi: 10.1093/jac/dkt045. Epub 2013 Feb 20.

New drugs for methicillin-resistant Staphylococcus aureus: an update.

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  • 1Skirball Institute Program in Molecular Pathogenesis and Department of Microbiology, New York University Medical Center, NY 10016, USA.


Methicillin-resistant Staphylococcus aureus (MRSA) remains a leading cause of bacterial infections worldwide, with a dwindling repertoire of effective antimicrobials active against it. This review aims to provide an update on novel anti-MRSA molecules currently under pre-clinical and clinical development, with emphasis on their mechanism of action. This review is limited to molecules that target the pathogen directly and does not detail immunomodulatory anti-infectives.


MRSA; antibiotics; mechanism of action

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