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JAMA. 2013 Feb 20;309(7):717-8. doi: 10.1001/jama.2013.697.

Clinical outcomes associated with procalcitonin algorithms to guide antibiotic therapy in respiratory tract infections.

Author information

  • 1Medical University Department, Kantonsspital Aarau, Tellstrasse, CH-5001 Aarau, Switzerland. schuetzph@gmail.com

Abstract

CLINICAL QUESTION:

In patients with respiratory tract infection, is measurement of procalcitonin to guide antibiotic prescriptions associated with reduced antibiotic exposure without increases in all-cause mortality or treatment failure?

BOTTOM LINE:

The measurement of procalcitonin to guide initiation and duration of antibiotic treatment in patients with respiratory tract infections of varying severity is associated with lower antibiotic exposure without increasing all-cause mortality or treatment failure.

PMID:
23423417
[PubMed - indexed for MEDLINE]
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