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J Asian Nat Prod Res. 2013;15(3):265-9. doi: 10.1080/10286020.2012.762764. Epub 2013 Feb 19.

Two new compounds from the metabolites of a marine-derived actinomycete Streptomyces cavourensis YY01-17.

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  • 1School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.


Our current marine natural product program investigated the second metabolites of an actinomycete Streptomyces cavourensis YY01-17 originating from the Antarctic ecological niche to discover potential antitumor chemical entities. Two new compounds, along with a known compound, were isolated from the ethyl acetate extract of the fermentation broth of the marine-derived actinomycete, and their structures were elucidated, respectively, as 2(S)-3'-hydroxybutan-2'-yl 2-hydroxypropanoate (1), (E)-3-hydroxy-2,4-dimethylhept-4-enamide (2), and 2-hydroxy-3-methylbutanoic acid (3) on the basis of spectroscopic data interpretation.

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