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Neurosci Res. 2013 Apr;75(4):269-74. doi: 10.1016/j.neures.2013.01.011. Epub 2013 Feb 15.

Molecular neuroimaging of emotional decision-making.

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  • 1Department of Psychiatry, Kyoto University Graduate School of Medicine, 54 Shogoin, Kawara-cho, Sakyo-ku, Kyoto 606-8507, Japan. hidehiko@kuhp.kyoto-u.ac.jp

Abstract

With the dissemination of non-invasive human neuroimaging techniques such as fMRI and the advancement of cognitive science, neuroimaging studies focusing on emotions and social cognition have become established. Along with this advancement, behavioral economics taking emotional and social factors into account for economic decisions has been merged with neuroscientific studies, and this interdisciplinary approach is called neuroeconomics. Past neuroeconomics studies have demonstrated that subcortical emotion-related brain structures play an important role in "irrational" decision-making. The research field that investigates the role of central neurotransmitters in this process is worthy of further development. Here, we provide an overview of recent molecular neuroimaging studies to further the understanding of the neurochemical basis of "irrational" or emotional decision-making and the future direction, including clinical implications, of the field.

Copyright © 2013 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.

PMID:
23419862
[PubMed - indexed for MEDLINE]
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