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BMJ Case Rep. 2013 Feb 13;2013. pii: bcr2012007668. doi: 10.1136/bcr-2012-007668.

The effect of high-intensity aerobic interval training on postinfarction left ventricular remodelling.

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  • 1Centre for Sports Medicine and Human Performance, School of Sport and Education, Brunel University, Uxbridge, UK. richard.godfrey@brunel.ac.uk

Abstract

This is the third in a series of case studies on an individual with normal coronaries who sustained an idiopathic acute myocardial infarction . Bilateral pulmonary emboli almost 2 years post-myocardial infarction (MI) revealed coagulopathy as the cause. The original MI resulted in 16% myocardial scar tissue. An increasing number of patients are surviving MI, hence the burden for healthcare often shifts to heart failure. Accumulating evidence suggests high-intensity aerobic interval exercise (AHIT) is efficacious in improving cardiac function in health and disease. However, its impact on MI scar has never been assessed. Accordingly, the 50-year-old subject of this case study undertook 60 weeks of regular AHIT. Successive cardiac MRI results demonstrate, for the first time, a decrease in MI scar with exercise and, alongside mounting evidence of high efficacy and low risk, suggests AHIT may be increasingly important in future prevention and reversing of disease and or amelioration of symptoms.

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