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Tijdschr Psychiatr. 2013;55(2):83-91.

[Risk factors for inactivity in patients in long-term care with severe mental illness].

[Article in Dutch]

Author information

  • 1CGZ Centraal, LocatieZon & Child, Amersfoort. de.tenback@ggzcentraal.nl

Abstract

BACKGROUND:

Inactivity is a major problem in long-stay patients with severe mental illness. Very little research has been done into the variables that can predict and explain this inactivity.

AIM:

To find associations between inactivity and the variables (psychiatric, pharmacological, lifestyle and comorbidity) of patients with severe mental health illness.<span class="abbreviation">methods </span>A cross-sectional study was performed at "Zon en Schild", a centre for mental health care in Amersfoort in the Netherlands. The study included 100 long-stay psychiatric patients hospitalized throughout the period February 2011 till July 2011. All of these patients were being treated with antipsychotics and were long-term inpatients at a psychiatric clinic. At the out-patient clinic of "Zon en Schild"; they were screened for inactivity via a subscale of the Nurses"; Observation Scale for Inpatient Evaluation (NOSIE-30). Data were collected and analysed by means of a validated questionnaire, physical examination and patient records. Simple and multiple regression analyses were performed in order to find associated factors associated with inactivity.

RESULTS:

We found that 31.3% of the variance predicted by the multiple regression analysis model for inactivity was associated with the variables parkinsonism, negative symptoms, metabolic syndrome, diabetes, body-mass index (BMI), first-generation antipsychotics and combination of first- and second-generation antipsychotics. Age (β=0.235, p=0.04) and a combination therapy involving traditional and atypical antipsychotics (β=0.317, p=0.04) were significantly associated with inactivity.

CONCLUSION:

Age and the combination of first- and second-generation antipsychotics were associated with inactivity. Cross-sectional studies do not demonstrate any causal links, but can generate a hypothesis. One possible hypothesis for the surprising link between inactivity and the combination of traditional and atypical antipsychotics is that the combination of antipsychotics promotes and fosters inactivity.<span class="abbreviation">key words</span> clinical, epidemiology, inactivity, long-term care, schizophrenia.

PMID:
23408360
[PubMed - indexed for MEDLINE]
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