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Org Biomol Chem. 2013 Mar 28;11(12):1925-8. doi: 10.1039/c3ob40094h. Epub 2013 Feb 14.

Copper-catalysed oxidative C-H/N-H cross-coupling between formamides and amides through chelation-assisted N-H activation.

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  • 1Key Laboratory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, West China Medical School, Sichuan University, 29 Wangjiang Road, Chengdu 610064, PR China.

Abstract

A copper-catalysed oxidative C-H/N-H cross-coupling between formamides and amides through chelation-assisted N-H activation has been developed for the preparation of various multi-substituted ureas.

PMID:
23407643
[PubMed - indexed for MEDLINE]
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