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Clin Appl Thromb Hemost. 2014 Jan;20(1):31-6. doi: 10.1177/1076029613476340. Epub 2013 Feb 12.

Relation of angiographic thrombus burden with electrocardiographic grade III ischemia in patients with ST-segment elevation myocardial infarction.

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  • 11Department of Cardiology, Mustafa Kemal University Medical School, Hatay, Turkey.

Abstract

BACKGROUND:

We aimed to investigate the association between electrocardiographic (ECG) grade III ischemia and angiographic thrombus burden in patients with acute ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (pPCI).

METHODS:

The study population consisted of 307 patients with STEMI. Baseline ECGs of the patients were analyzed for grade III ischemia; angiographic thrombus burden was assessed by thrombolysis in myocardial infarction thrombus classification.

RESULTS:

A total of 108 (35%) patients had low thrombus burden whereas 199 (65%) patients had high thrombus burden. Grade III ischemia was more prevalent in patients with high thrombus burden (25.1% vs 11.1%, P = .004). Only grade III ischemia (odds ratio: 2.59, 95% confidence interval 1.24-5.39, P = .011) and history of coronary artery disease (CAD) were found to be the independent predictors of high thrombus burden.

CONCLUSION:

Grade III ischemia on ECG and previous history of CAD were independent predictors of coronary thrombus burden in patients with STEMI who underwent pPCI.

KEYWORDS:

ST-elevation myocardial infarction; grade III ischemia; thrombus burden

[PubMed - indexed for MEDLINE]
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