Is there a role for the detection of autoantibodies in the clinical practice of treating infants with bullous pemphigoid? A case report

Pediatr Dermatol. 2014 Nov-Dec;31(6):748-9. doi: 10.1111/pde.12082. Epub 2013 Feb 14.

Abstract

We present a case of infantile bullous pemphigoid (BP) triggered by primary infection with varicella zoster virus and we analyze the correlation between autoantibody levels and disease activity. With this report we suggest that serum autoantibody titers may not necessarily mirror the clinical course of the disease or represent a helpful tool in guiding therapeutic decisions in infantile BP.

Publication types

  • Case Reports

MeSH terms

  • Autoantibodies / blood*
  • Chickenpox / complications
  • Glucocorticoids / therapeutic use
  • Humans
  • Immunoglobulin G / blood
  • Infant
  • Male
  • Methylprednisolone / therapeutic use
  • Pemphigoid, Bullous / blood*
  • Pemphigoid, Bullous / drug therapy*
  • Prednisone / therapeutic use

Substances

  • Autoantibodies
  • Glucocorticoids
  • Immunoglobulin G
  • Prednisone
  • Methylprednisolone