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Orv Hetil. 2013 Feb 3;154(5):172-7. doi: 10.1556/OH.2013.29540.

[Anthropometric data, fetal and neonatal complications in infants of diabetic mothers. Results of a 10-year retrospective study].

[Article in Hungarian]

Author information

  • 1Pándy Kálmán Megyei Kórház Gyermekosztály Gyula Kárpát u. 11. 5700. hajdukati.gyk@pandy.hu

Abstract

INTRODUCTION:

Disturbances in carbohydrate metabolism during pregnancy may result in harmful fetal and neonatal consequences.

OBJECTIVES:

To assess the fetal and neonatal complications of pregnancy in mothers with gestational and pregestational diabetes during a 10-year period in a county hospital in Hungary.

METHODS:

Retrospective analysis of infants of diabetic mothers admitted to the neonatal unit between 2001 and 2010.

RESULTS:

32% of the infants were transferred to the neonatal unit. Neonatal macrosomia (birth weight >90 centile) was observed in one quarter of the infants. 39% of the infants developed hypoglycemia (blood glucose <2.6 mmol/l), in the majority of the cases within the first 8 hours. Hypoglycaemia was symptomatic in 55% of the infants. Hypocalcemia was observed in 17%, hyperviscosity in 23%, hyperbilirubinaemia in 32%, respiratory distress syndrome and/or transient tachypnoe in 22% and cardiac complications in 13% of the infants. 10% of the inafnts were affected with birth injuries. Congenital anomalies were seen in 17% of the cases, and severe malformations were present in 4% of the infants.

CONCLUSIONS:

Despite modern diabetes management, there is still a higher incidence of fetal macrosomia, adverse neonatal outcomes and a higher rate of severe congenital malformations in neonates of diabetic mothers.

PMID:
23395742
[PubMed - indexed for MEDLINE]
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