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Org Lett. 2013 Mar 1;15(5):1000-3. doi: 10.1021/ol3034466. Epub 2013 Feb 8.

Nardoaristolones A and B, two terpenoids with unusual skeletons from Nardostachys chinensis Batal.

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  • 1Institute of Traditional Chinese Medicine & Natural Products, Jinan University, Guangzhou 510632, People's Republic of China.


Nardoaristolones A and B, two novel terpenoids derived from the aristolane-type sesquiterpenoid, were isolated from the underground parts of Nardostachys chinensis Batal. Nardoaristolone A is the first reported aristolane-chalcone derivative, while nardoaristolone B possesses a nor-aristolane sesquiterpenoid skeleton with an unusual 3/5/6 tricyclic ring system. Their structures were elucidated by spectroscopic measurements, and the absolute configurations were established by single-crystal X-ray diffraction experiments.

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