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Clin Rheumatol. 2013 May;32(5):645-8. doi: 10.1007/s10067-013-2163-0. Epub 2013 Feb 5.

Leprosy with ANA positive mistaken for connective tissue disease.

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  • 1Department of family medicine, Sir Run Run Shaw Hospital, Zhejiang University, Qingchun Road No.3, Hangzhou 310016, China.


Leprosy is associated with the occurrence of various skin lesions such as macules, papules, plaques, nodules, and even diffused infiltration, depending on the patient's immune response. Its clinical presentation is often different from the usual pattern, leading to confusion in diagnosis. We present a case of leprosy with ANA positive that was mistaken for connective tissue disease. In this case, we want to tell that doctors should not only depend on laboratory index for diagnosis, the misdiagnosis may lead to delaying illness and aggravating illness.

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