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Z Med Phys. 2013 Sep;23(3):228-35. doi: 10.1016/j.zemedi.2013.01.001. Epub 2013 Feb 4.

Grating-based darkfield imaging of human breast tissue.

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  • 1Erlangen Centre for Astroparticle Physics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erwin-Rommel-Str. 1, 91058 Erlangen, Germany.


Mastectomy specimens were investigated using a Talbot-Lau X-ray imaging set-up. Significant structures in the darkfield were observed, which revealed considerably higher contrast than those observed in digital mammography. Comparison with the histomorphometric image proofs that the darkfield signal correlates with a tumor region containing small calcification grains of 3 to 30μm size.

Copyright © 2013. Published by Elsevier GmbH.


Brustkrebs; Dunkelfeldbildgebung; Mammographie; Mikrokalzifikation; Röntgenbildgebung; Talbot-Lau; X-ray imaging; breast cancer; darkfield imaging; mammography; microcalcification

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