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Perit Dial Int. 2013 Jul-Aug;33(4):405-10. doi: 10.3747/pdi.2012.00018. Epub 2013 Feb 1.

Geriatric Nutritional Risk Index as a prognostic factor in peritoneal dialysis patients.

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  • 1Division of Nephrology, Department of Internal Medicine, Yeungnam University Hospital, Daegu, Korea.

Abstract

BACKGROUND:

The Geriatric Nutritional Risk Index (GNRI) might be a useful screening tool for malnutrition in dialysis patients. However, data concerning the GNRI as a prognostic factor in peritoneal dialysis (PD) patients are scarce.

METHODS:

We reviewed the medical records at Yeungnam University Hospital in Korea to identify all adults (>18 years) who received PD; 486 patients were enrolled in the study.

RESULTS:

The initial low, middle, and high GNRI tertiles included 162, 166, and 158 patients respectively. Significant correlations were noted between the initial GNRI and body mass index, creatinine, albumin, arm circumference, fat mass index, and comorbidities. The cut-off value for the time-averaged GNRI over 1 year was 96.4, and the sensitivity and specificity for a diagnosis of a decline in lean mass were 77.1% and 40.0% respectively. A multivariate analysis adjusted for age, risk according to the Davies comorbidity index, and C-reactive protein showed that an low initial GNRI tertile was associated with mortality in PD patients.

CONCLUSIONS:

The GNRI is a simple method for predicting nutrition status and clinical outcome in PD patients.

KEYWORDS:

Geriatric Nutritional Risk Index; lean mass; nutrition; prognostic factor

PMID:
23378470
[PubMed - indexed for MEDLINE]
PMCID:
PMC3707719
Free PMC Article
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