Send to

Choose Destination
See comment in PubMed Commons below
Nervenarzt. 2013 Feb;84(2):229-44. doi: 10.1007/s00115-012-3701-8.

[Current cerebrospinal fluid diagnostics for pathogen-related diseases].

[Article in German]

Author information

  • 1Abteilung für Neurologie, Universitätsklinikum Ulm, Uniklinik im RKU, Oberer Eselsberg 45, 890875, Ulm, Deutschland.


Cerebrospinal fluid (CSF) analysis is of utmost importance to establish an early diagnosis of central nervous system (CNS) infections and to start appropriate therapy. The CSF white cell count, lactate concentration and total protein levels are usually available very quickly even from non-specialized laboratories and the combination of these parameters often provides sufficient information for decision-making in emergency cases. It is, however, not always possible to identify the underlying infective agent despite further CSF analyses, such as bacterial and fungal staining, evaluation of the blood-CSF barrier function, intrathecal immunoglobulin synthesis and oligoclonal IgG bands. Therefore, close communication between the laboratory and the clinician is an important prerequisite to specify additional pathogen-related diagnostic measures for successful confirmation of the diagnosis.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Springer
    Loading ...
    Write to the Help Desk