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Department of Pathology, Indiana University School of Medicine, Indianapolis.
Palisading necrobiotic granulomas of the prostate are an uncommon but well-recognized sequela of transurethral surgery. Similar granulomas occurring in 3 patients after transurethral surgery of the urinary bladder are reported. In each case, the lesions were discovered as a result of biopsies done subsequent to transurethral resections of bladder tumors. An idiosyncratic hypersensitivity reaction to a diathermically induced change in the antigenicity of the subepithelial connective tissue is suggested as the cause of these granulomas.
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