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Hautarzt. 2013 Feb;64(2):107-9. doi: 10.1007/s00105-012-2477-x.

[Herpes zoster after varicella-zoster vaccination].

[Article in German]

Author information

  • 1HELIOS Klinikum Wuppertal. marion.fahlbusch@helios-kliniken.de

Abstract

A five-year-old girl, vaccinated against varicella-zoster virus (VZV) presented with clinical symptoms of herpes zoster in the 6th cervical dermatome. A VZV direct immune-fluorescence assay was negative three times but additional genotypical analysis showed a VZV strain genotype 2 (Oka vaccine strain). Therefore the diagnosis of a breakthrough varicella disease with the vaccine strain was established. An immunodeficiency was ruled out and the patient responded well to the initiated therapy. This case demonstrates that a negative VZV direct immunofluorescence assay does not exclude an infection with the vaccine strain.

PMID:
23358727
[PubMed - indexed for MEDLINE]
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