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World J Hepatol. 2012 Dec 27;4(12):394-8. doi: 10.4254/wjh.v4.i12.394.

Acute abdomen and ascites as presenting features of autosomal dominant polycystic kidney disease.

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  • 1Sanjay Chaudhary, Qi Qian, Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, United States.


We describe a patient with sudden onset of abdominal pain and ascites, leading to the diagnosis of autosomal dominant polycystic kidney disease (ADPKD). Her presentation was consistent with acute liver cyst rupture as the cause of her acute illness. A review of literature on polycystic liver disease in patients with ADPKD and current management strategies are presented. This case alerts physicians that ADPKD could occasionally present as an acute abdomen; cyst rupture related to ADPKD may be considered in the differential diagnoses of acute abdomen.


Acute abdominal pain; Ascites; Autosomal dominant polycystic kidney disease; Polycystic liver disease

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