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Genomics. 1990 May;7(1):123-6.

Mapping of the thrombospondin gene to human chromosome 15 and mouse chromosome 2 by in situ hybridization.

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  • 1Department of Pathology, University of Washington, Seattle 98195.


We have mapped the thrombospondin gene (THBS1) to a single locus on human chromosome 15 (band q15) and on mouse chromosome 2 (region F). Thrombospondin has been implicated in a variety of cell-matrix and cell-cell interactions. The finding of a single locus suggests that the different functions of thrombospondin are not due to a closely related family of genes. These results also confirm a region of homology between the proximal part of human chromosome 15 and region F of mouse chromosome 2.

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