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BMJ Case Rep. 2013 Jan 22;2013. pii: bcr2012008153. doi: 10.1136/bcr-2012-008153.

Pseudomembranous colitis due to Clostridium difficile as a cause of perineal necrotising fasciitis.

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  • 1Service d'Urgence Respiratoire, Réanimation Médicale et Medecine Hyperbare, Université de Lille II et Centre Hospitalier et Universitaire de Lille, Lille, France.


Although rare, pseudomembranous colitis may be a cause of perineal necrotising fasciitis in a context of immunosuppression, as in the case we report. This origin must be quickly identified because the therapeutic management, especially surgery, is unlikely to be the same as usual. Similarly, antibiotic treatment is also a matter of discussion due to the potential deleterious role of antibiotics in pseudomembranous colitis.

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