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Indian Pacing Electrophysiol J. 2013 Jan;13(1):14-33. Epub 2013 Jan 1.

Radiofrequency catheter ablation of idiopathic right ventricular outflow tract arrhythmias.

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  • 1Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.


Idiopathic ventricular arrhythmias (VA) consist of various subtypes of VA that occur in the absence of clinically apparent structural heart disease. Affected patients account for approximately 10% of all patients referred for evaluation of ventricular tachycardia (VT). Arrhythmias arising from the outflow tract (OT) are the most common subtype of idiopathic VA and more than 70-80% of idiopathic VTs or premature ventricular contractions (PVCs) originate from the right ventricular (RV) OT. Idiopathic OT arrhythmias are thought to be caused by adenosine-sensitive, cyclic adenosine monophosphate (cAMP) mediated triggered activity and, in general, manifest at a relatively early age. Usually they present as salvos of paroxysmal ventricular ectopic beats and are rarely life-threatening. When highly symptomatic and refractory to antiarrhythmic therapy or causative for ventricular dysfunction, ablation is a recommended treatment with a high success rate and a low risk of complications.


ICDs; ablation; outflow tract; premature ventricular contractions; ventricular arrhythmias

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