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Acta Neurol Taiwan. 2012 Dec;21(4):165-8.

Olanzapine treatment for tics in an adult woman with severe tourette syndrome.

Author information

  • 1Department of Neurology, National Cheng Kung University College of Medicine and Hospital, Tainan, Taiwan. wjhwang@mail.ncku.edu.tw

Abstract

PURPOSE:

Olanzapine had been reported to be effective in the control of tics in a few adult female patients who had a short follow-up period. The author reports the successful outcome of long-term olanzapine treatment in an adult woman with severe Tourette syndrome.

CASE REPORT:

A 33-year-old woman who had severe motor and vocal tics (Modified Rush Videotape Rating Scale: 17/20) showed an excellent response to olanzapine 10 mg/day within 2 months. Her tic symptoms were well controlled with gradual reduction of her dose of olanzapine to 2.5 mg/day during the following 8 years. She was symptom-free without medications in the past 2 years. In addition, she had a normal menstrual cycle and became pregnant during the period of olanzapine treatment.

CONCLUSION:

Olanzapine may be the drug of first choice for treating severe Tourette syndrome in pubescent female adolescents and young women who wish to have children.

PMID:
23329547
[PubMed - indexed for MEDLINE]
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