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J Asian Nat Prod Res. 2013;15(2):203-8. doi: 10.1080/10286020.2012.751977. Epub 2013 Jan 17.

A new compound from liquid fermentation broth of Armillaria mellea and the determination of its absolute configuration.

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  • 1Institute of Genetics and Cytology, Northeast Normal University, Renmin Street 5268, Changchun 130024, China.


A new 2,5-diketopiperazine, (R)-2-(2-(furan-2-yl)-oxoethyl)-octahydropyrrolo[1,2-a]pyrazine-1,4-dione, and seven known compounds were isolated from the ethyl acetate extract of liquid fermentation broth of Armillaria mellea. The structures of the isolated compounds were established from NMR and HR-MS data. The absolute configuration of the new compound was established by comparing the experimental electronic circular dichroism (ECD) spectrum with the calculated ECD data.

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