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Ther Deliv. 2012 Dec;3(12):1457-67. doi: 10.4155/tde.12.132.

Micro- and nano-fabricated implantable drug-delivery systems.

Author information

  • 1Department of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089-1111, USA. ellis.meng@usc.edu

Abstract

Implantable drug-delivery systems provide new means for achieving therapeutic drug concentrations over entire treatment durations in order to optimize drug action. This article focuses on new drug administration modalities achieved using implantable drug-delivery systems that are enabled by micro- and nano-fabrication technologies, and microfluidics. Recent advances in drug administration technologies are discussed and remaining challenges are highlighted.

PMID:
23323562
[PubMed - indexed for MEDLINE]
PMCID:
PMC3576846
Free PMC Article

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