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J Comput Assist Tomogr. 2013 Jan-Feb;37(1):79-83. doi: 10.1097/RCT.0b013e318278e996.

Reduction of interpatient variability of arterial enhancement using a new bolus tracking system in 320-detector computed tomographic coronary angiography.

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  • 1Department of Diagnostic Radiology, Hiroshima University, 1-2-3 Kasumi, Hiroshima, Japan.



To investigate the effect of a new bolus tracking system on interpatient variability of aortic and coronary enhancement compared with the conventional system in 320-detector computed tomographic (CT) coronary angiography (CTCA).


Sixty-four patients who underwent CTCA were assigned to 1 of 2 protocols. In group A (n = 32), 7 seconds after triggering (150-Hounsfield unit [HU] threshold) in the ascending aorta, a CT scan was performed. In group B (n = 32), 2 thresholds were set in the ascending aorta. After the first triggering (100 HU threshold), the patient was instructed to take a breath and hold it. Approximately 3 seconds after the second triggering (300 HU threshold), a CT scan was started automatically.


There were no significant differences in the mean CT attenuation for the ascending aorta between the 2 groups (P = 0.61), whereas the standard deviation of the CT attenuation in group B was significantly smaller than that in group A (P = 0.02).


The use of a 2-threshold setting in the new bolus tracking technique could reduce interpatient variability more than a protocol using a single threshold in CTCA.

[PubMed - indexed for MEDLINE]
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