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Zhong Yao Cai. 2012 Aug;35(8):1263-7.

[Study on the chemical components, antimicrobial and antitumor activities of the essential oil from the leaves of Zanthoxylum avicennae].

[Article in Chinese]

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  • 1Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, Haikou 571158, China.

Abstract

OBJECTIVE:

To study the chemical constituents, antimicrobial activity and antitumor activity of the essential oil from Zanthoxylum avicennae.

METHODS:

The essential oil from the leaves of Zanthoxylum avicennae was extracted by steam distillation. The components of the essential oil were separated and identified by GC-MS.

RESULTS:

72 components were identified and accounted for 98.15% of the all peak area. The essential oil exhibited strong antitumor activity against K-562 human tumor cell lines with IC50 of 1.76 microg/mL. It also exhibited moderate antimicrobial activity against three bacteria.

CONCLUSION:

The essential oil of Zanthoxylum avicennae contains various active constituents. This result provides scientific reference for the pharmacological further research of Zanthoxylum avicennae.

PMID:
23320360
[PubMed - indexed for MEDLINE]
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