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J Clin Aesthet Dermatol. 2013 Jan;6(1):39-46.

Is there a true concern regarding the use of hair dye and malignancy development?: a review of the epidemiological evidence relating personal hair dye use to the risk of malignancy.

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  • 1Drs. Saitta, Grekin, and Holland are from the Department of Dermatology, Oakwood Southshore Medical Center, Trenton, Michigan; Dr. Cook is from the Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida; Dr. Messina is from the Departments of Pathology, Dermatology & Cutaneous Surgery, University of South Florida, Tampa, Florida; Dr. Brancaccio is from the Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York; Mr. Wu is from the University of Medicine and Dentistry of New Jersey-Graduate School of Biomedical Sciences, Stratford, New Jersey.


Many advances in the cosmetic industry have increased our ability to enhance youth and beauty. Hair-coloring products are one such innovation. Over the past several decades, a significant amount of work has been dedicated to understanding the possible long-term side effects associated with hair-dye use, specifically looking at cancer risk. This paper describes the hair-coloring process, highlights the potentially carcinogenic ingredients in various hair-dying products, and reviews the epidemiological evidence relating personal hair-dye use to the risk of developing several types of malignancies.

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