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Structure. 2013 Jan 8;21(1):6-8. doi: 10.1016/j.str.2012.12.003.

One protein, at least three structures, and many functions.

Author information

  • 1Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN 47401, USA. azlotnic@indiana.edu

Abstract

Hepatitis B virus core gene products can adopt different conformations to perform their functional roles. In this issue of Structure, DiMattia and colleagues show the crystal structure of immuno-modulating HBeAg and thereby reveal the similarities and differences between it and HBcAg, the variant found in virions.

Copyright © 2013 Elsevier Ltd. All rights reserved.

PMID:
23312031
[PubMed]
PMCID:
PMC3545281
Free PMC Article
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